PATHOS: European harmonised large scale patient-oriented PATHOgenesis research Studies in response to severe ID outbreaks
PATHOS is PREPARE’s flexible multidisciplinary platform for the rapid deployment of European harmonised large scale patient-oriented PATHOgenesis research Studies in response to severe ID outbreaks using a systems medicine approach. PATHOS is aimed at identifying the relative contributions of host- and pathogen factors to development of severe disease across different aetiologies, ages and clinical backgrounds. Such pathophysiological insights are central to development of effective clinical management strategies during severe ID outbreaks.