BMC Medicine - 2019 Authors: Sigfrid, L., Perfect, C., Rojek, A., Longuere, K.S., Lipworth, S., Harriss, E., Lee, J., Salam, A., Carson, G., Goossens, H., Horby, P.  Abstract  The epidemiology of CNS infections in Europe is dynamic, requiring that clinicans have access to up-to-date clinical management guidelines (CMGs) to aid identification of emerging i... read more

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ERJ open research - May 2019 Authors: Gobat N., Amuasi J., Yazdanpanah Y., Sigfrid L., Davies H., Byrne J.-P., Carson G., Butler C., Nichol A., Goossens H. Conlusion Being ready to deliver clinically useful research in the narrow timeframe available during an infectious disease epidemic requires pre-planning pre-positioning and practice of research responses. ... read more

ECRAID-Plan Presentation Authors: Goossens H., Bonten M. Kicking off on January 17th 2019 with a high-level meeting in Brussels, PREPARE and COMBACTE will commence the development of the business plan for ECRAID, the European Clinical Research Alliance on Infectious Diseases. ECRAID envisages a European-wide sustainable clinical research organization for infect... read more

The Lancet - November 2018 Authors: Gobat N., van Someren Gréve F., Sigfrid L., Reusken C. B., Deege F., Carson G., Horby P., Koopmans M., de Jong M. D., Goossens H. Meeting abstract A new or re-emerging infectious disease pandemic ranks among the highest priorities for civic contingency planning. Despite advances in preclinical and clinical research methods... read more

The Lancet - November 2018 Authors: Gobat N., Butler C. C., Harris V., Gal M., Francis N. A., Mollison J., Byrne J.-P., Watkins A., Hood K., Moore R., Sukumar P., Webb S. A. R., Nichol A. Meeting Abstract Patients and the public are primary beneficiaries and contributors to pandemic-relevant clinical research. We aimed to understand their views about participat... read more

Clinical Microbiology and Infection - March 2018  Authors: Reusken C.B., Ieven M., Sigfrid L., Eckerle I., Koopmans M.  Abstract The global health burden of arboviruses is continuously rising, which results in increasing pressure on local and (inter)national laboratory infrastructures. Timely and accurate diagnosis of cases is one of the main pillars for ... read more

Clinical Microbiology and Infectious - March 2018 Authors: Sigfrid L., Reusken C., Eckerle I., Nussenblatt V., Lipworth S., Messina J., Kraemer M., Ergonul O., Papa A., Koopmans M., Horby P. Abstract Arthropod-borne virus (Arbovirus) infections are considered an emerging threat for Europe, with an increase in cases in recent decades. The increase in global travel a... read more

Clinical Microbiology and Infection - March 2018  Authors: Eckerle I., Briciu V.T., Ergönül Ö., Papa A., Radulescu A., Tsiodras S., Tsitou C., Drosten C., Nussenblatt V.R., Reusken C.B., Sigfrid L., Beeching N.J.  Abstract Arboviruses are an emerging group of viruses that are causing increasing health concerns globally, including in Europe.... read more

Biomedical Journal of Scientific & Technical Research  - May 2018  Authors: Adeoti A.O., Ojiaku O., Sigfrid L.  Abstract Despite the discovery of Lassa fever nearly five decades ago, the disease is still endemic in West Africa. The Nigerian Centre for Disease Control’s (NCDC) weekly epidemiological report for the first 10 weeks in the ... read more