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Key stakeholder perceptions about consent to participate in acute illness research

Entered on 08-01-2016

The WP1 team published a rapid, systematic review to inform epi/pandemic research preparedness

First report on EARL hurdles for research in the European Union.

Entered on 18-12-2015

A first report of a provider and a user assessment of ethical, administrative, regulatory and logistical (EARL) hurdles for research in the European Union was completed.  EARL report - Part A EARL report - Part B

The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis

Entered on 04-11-2015

Host genetic factors have frequently been implicated in respiratory infectious diseases, often with inconsistent results in replication studies. We identified 386 studies from the total of 24,823 studies identified in a systematic search of four bibliographic databases. We performed meta-analyses of studies on tuberculosis, influenza, respiratory syncytial virus, SARS... read more

Interview with Chris Butler (ALIC4E) regarding the use of antivirals during a pandemic

Entered on 16-10-2015

Together with the Wellcome Trust, Professor Chris Butler and his team reviewed all recent evidence on the use of Tamiflu during a flu pandemic. Read his recommendations on the use of antivirals on the BBC website or download the full article.

Human bocavirus infection as a cause of severe acute respiratory tract infection in children.

Entered on 09-07-2015

In 2005 human bocavirus (HBoV) was discovered in respiratory tract samples of children. The role of HBoV as single causative agent for respiratory tract infections remains unclear. Detection of HBoV in children with respiratory disease is frequently in combination with other viruses or bacteria. We set up an algorithm to study whether HBoV alone can cause severe acute... read more

Antigenic maps of influenza A/H3N2 virus produced with human antisera obtained after primary infection

Entered on 09-07-2015

Antigenic characterization of influenza viruses is typically based on hemagglutination inhibition (HI) assay data of viral isolates tested against strain-specific post-infection ferret antisera. Here, similar virus characterizations were performed using first-infection human rather than ferret serology data. Download publication read more

Genome-wide longitudinal analysis of emm1 invasive Group A Streptococcus isolated from Belgian patients during 1994˗2013

Entered on 30-04-2015

ECCMID 2015, 25-28 April, Copenhagen, Denmark - presentation Download publication

High Resolution Clonality of Outbreak-Causing Acinetobacter baumannii studied by Whole Genome Mapping

Entered on 30-04-2015

ECCMID 2015, 25-28 April, Copenhagen, Denmark - poster Download publication

Preparedness for Admission of patients with suspected ebola virus disease in European hospitals: a survey, August-September 2014

Entered on 31-03-2015

In response to the Ebola virus disease (EVD) outbreak in West Africa, the World Health Organization has advised all nations to prepare for the detection, investigation and management of confirmed and suspected EVD cases in order to prevent further spread through international travel. To gain insights into the state of preparedness of European hospitals, an electronic ... read more

Whole genome mapping as a fast-track tool to assess genomic stability of sequenced Staphylococcus aureus strains

Entered on 21-10-2014

Whole genome (optical) mapping (WGM), a state-of-the-art mapping technology based on the generation of high resolution restriction maps, has so far been used for typing clinical outbreak strains and for mapping de novo sequence contigs in genome sequencing projects. We employed WGM to assess the genomic stability of previously sequenced Staphylococcus aureus strains t... read more

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